Ultrasound surgery -- healing without cuts - Yoav Medan
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[Applause]
for<00:00:16.199> the<00:00:16.680> last<00:00:17.039> 13<00:00:17.480> years<00:00:18.119> 1<00:00:18.439> three<00:00:18.800> 13<00:00:19.240> years
for the last 13 years 1 three 13 years
for the last 13 years 1 three 13 years
I've<00:00:20.000> been<00:00:20.240> part<00:00:20.400> of<00:00:20.560> an<00:00:20.760> exceptional<00:00:21.240> team<00:00:21.439> at
I've been part of an exceptional team at
I've been part of an exceptional team at
Insite<00:00:21.960> Tech<00:00:22.160> in<00:00:22.359> Israel<00:00:23.359> and<00:00:23.599> partners
Insite Tech in Israel and partners
Insite Tech in Israel and partners
around<00:00:24.439> the<00:00:24.599> world<00:00:25.279> for<00:00:25.599> taking<00:00:26.199> this<00:00:26.400> idea
around the world for taking this idea
around the world for taking this idea
this<00:00:27.080> concept<00:00:28.080> non-invasive<00:00:28.960> surgery<00:00:30.000> from
this concept non-invasive surgery from
this concept non-invasive surgery from
the<00:00:30.279> research<00:00:30.759> lab<00:00:31.519> to<00:00:31.720> routine<00:00:32.160> clinical<00:00:32.640> use
the research lab to routine clinical use
the research lab to routine clinical use
and<00:00:33.399> this<00:00:33.520> is<00:00:33.760> what<00:00:33.920> I'll<00:00:34.160> tell<00:00:34.320> you<00:00:34.520> about<00:00:34.920> 13
and this is what I'll tell you about 13
and this is what I'll tell you about 13
years<00:00:36.239> for<00:00:36.480> some<00:00:36.640> of<00:00:36.800> you<00:00:37.160> they<00:00:37.320> can<00:00:37.559> empathize
years for some of you they can empathize
years for some of you they can empathize
with<00:00:38.760> that<00:00:38.960> number<00:00:39.760> for<00:00:39.960> me<00:00:40.280> today<00:00:40.680> on<00:00:40.879> this
with that number for me today on this
with that number for me today on this
stage<00:00:41.360> it's<00:00:41.520> like<00:00:41.680> a<00:00:41.840> second<00:00:42.160> Bar<00:00:42.399> Mitzvah
experience<00:00:46.399> yeah<00:00:47.399> so<00:00:48.039> so<00:00:49.039> this<00:00:49.440> this<00:00:49.800> dream<00:00:50.680> is
experience yeah so so this this dream is
experience yeah so so this this dream is
really<00:00:51.120> enabled<00:00:52.039> by<00:00:52.440> the<00:00:52.800> convergence<00:00:53.800> of<00:00:54.000> two
really enabled by the convergence of two
really enabled by the convergence of two
known<00:00:54.719> Technologies<00:00:55.719> one<00:00:55.879> is<00:00:56.039> the<00:00:56.199> force<00:00:56.520> of
known Technologies one is the force of
known Technologies one is the force of
ultrasound<00:00:57.960> and<00:00:58.079> the<00:00:58.239> other<00:00:58.480> one<00:00:58.960> is<00:00:59.160> the
ultrasound and the other one is the
ultrasound and the other one is the
vision<00:01:00.399> enabled<00:01:01.000> by<00:01:01.320> magnetic<00:01:02.120> resonance
vision enabled by magnetic resonance
vision enabled by magnetic resonance
imaging<00:01:04.199> so<00:01:04.439> let's<00:01:05.040> first<00:01:05.360> talk<00:01:05.600> about<00:01:06.000> Focus
imaging so let's first talk about Focus
imaging so let's first talk about Focus
ultrasound<00:01:08.200> and<00:01:08.439> I<00:01:08.680> hold<00:01:08.960> in<00:01:09.159> my<00:01:09.360> hand<00:01:09.960> the
ultrasound and I hold in my hand the
ultrasound and I hold in my hand the
tissue<00:01:10.400> mimicking<00:01:10.920> Phantom<00:01:11.560> it<00:01:11.640> is<00:01:11.799> made<00:01:12.000> out
tissue mimicking Phantom it is made out
tissue mimicking Phantom it is made out
of<00:01:12.360> silicon<00:01:13.320> it<00:01:13.439> is
of silicon it is
of silicon it is
transparent<00:01:15.680> uh<00:01:16.119> made<00:01:16.360> just<00:01:16.560> for<00:01:16.759> you<00:01:17.040> so<00:01:17.200> you
transparent uh made just for you so you
transparent uh made just for you so you
see<00:01:17.680> it's<00:01:17.920> all<00:01:18.960> intact<00:01:19.960> completely
see it's all intact completely
see it's all intact completely
transparent<00:01:21.360> okay<00:01:22.280> I'll<00:01:22.479> take<00:01:22.640> you<00:01:22.840> now<00:01:23.079> to
transparent okay I'll take you now to
transparent okay I'll take you now to
the<00:01:23.400> acoustic<00:01:23.960> lab<00:01:24.360> you<00:01:24.520> see<00:01:24.880> the<00:01:25.040> Phantom
the acoustic lab you see the Phantom
the acoustic lab you see the Phantom
within<00:01:25.920> the<00:01:26.079> aquarium<00:01:26.680> this<00:01:26.799> is<00:01:27.079> a<00:01:27.240> setup<00:01:27.720> I
within the aquarium this is a setup I
within the aquarium this is a setup I
put<00:01:28.159> in<00:01:28.280> the<00:01:28.439> physics<00:01:28.840> lab<00:01:29.280> on<00:01:29.439> the<00:01:29.600> right<00:01:30.000> hand
put in the physics lab on the right hand
put in the physics lab on the right hand
side<00:01:30.640> you<00:01:30.759> see<00:01:30.960> an<00:01:31.119> ultrasonic<00:01:32.159> transducer<00:01:33.159> so
side you see an ultrasonic transducer so
side you see an ultrasonic transducer so
the<00:01:33.600> ultrasonic<00:01:34.479> transducer<00:01:35.399> emits
the ultrasonic transducer emits
the ultrasonic transducer emits
basically<00:01:36.920> an<00:01:37.079> ultrasonic<00:01:37.680> beam<00:01:38.040> that
basically an ultrasonic beam that
basically an ultrasonic beam that
focuses<00:01:39.520> inside<00:01:40.119> the<00:01:40.600> Phantom<00:01:41.600> okay<00:01:41.840> when<00:01:41.960> you
focuses inside the Phantom okay when you
focuses inside the Phantom okay when you
hear<00:01:42.320> the
hear the
hear the
click<00:01:44.840> this<00:01:44.960> is<00:01:45.119> when<00:01:45.399> the<00:01:45.560> Energy<00:01:46.079> starts<00:01:46.399> to
click this is when the Energy starts to
click this is when the Energy starts to
Emit<00:01:47.240> and<00:01:47.360> you<00:01:47.520> see<00:01:48.119> a<00:01:48.320> lesion<00:01:48.799> formed<00:01:49.799> inside
Emit and you see a lesion formed inside
Emit and you see a lesion formed inside
the
the
the
Phantom<00:01:52.240> okay<00:01:53.040> so<00:01:53.880> everything<00:01:54.280> around<00:01:54.640> it<00:01:55.479> is
Phantom okay so everything around it is
Phantom okay so everything around it is
whole<00:01:56.159> and<00:01:56.399> intact<00:01:57.119> it's<00:01:57.320> just<00:01:57.640> lesion<00:01:58.000> formed
whole and intact it's just lesion formed
whole and intact it's just lesion formed
inside<00:01:58.759> so<00:01:59.039> think<00:01:59.280> about<00:01:59.960> this<00:02:00.079> is<00:02:00.240> in<00:02:00.360> your
inside so think about this is in your
inside so think about this is in your
brain<00:02:01.280> we<00:02:01.399> need<00:02:01.560> to<00:02:01.680> reach<00:02:01.880> a<00:02:02.039> Target<00:02:02.399> inside
brain we need to reach a Target inside
brain we need to reach a Target inside
the<00:02:02.880> brain<00:02:03.479> we<00:02:03.600> can<00:02:03.799> do<00:02:03.960> it<00:02:04.159> without<00:02:04.520> harming
the brain we can do it without harming
the brain we can do it without harming
any<00:02:05.840> tissue<00:02:06.840> so<00:02:07.560> this<00:02:07.759> is<00:02:08.080> I<00:02:08.160> think<00:02:08.399> the<00:02:08.560> first
any tissue so this is I think the first
any tissue so this is I think the first
kosher<00:02:09.720> Hippocratic<00:02:10.720> surgical
kosher Hippocratic surgical
kosher Hippocratic surgical
system<00:02:13.000> okay<00:02:13.239> so<00:02:13.680> so<00:02:14.120> let's<00:02:14.280> talk<00:02:14.440> a<00:02:14.560> little
system okay so so let's talk a little
system okay so so let's talk a little
bit<00:02:14.920> about<00:02:15.239> ultrasound<00:02:15.879> the<00:02:16.000> force<00:02:16.239> of
bit about ultrasound the force of
bit about ultrasound the force of
ultrasound<00:02:18.080> you<00:02:18.200> know<00:02:18.400> all<00:02:18.640> about<00:02:19.000> Imaging
ultrasound you know all about Imaging
ultrasound you know all about Imaging
right<00:02:19.840> ultrasound<00:02:20.440> imaging<00:02:20.920> and<00:02:21.040> you<00:02:21.200> know
right ultrasound imaging and you know
right ultrasound imaging and you know
also<00:02:21.760> about<00:02:22.000> loty<00:02:22.879> right<00:02:23.560> breaking<00:02:24.560> uh
also about loty right breaking uh
also about loty right breaking uh
breaking<00:02:25.879> kidney<00:02:26.319> stones<00:02:27.319> but<00:02:27.560> ultrasound
breaking kidney stones but ultrasound
breaking kidney stones but ultrasound
can<00:02:28.440> be<00:02:28.840> shaved<00:02:29.959> to<00:02:30.160> be<00:02:31.080> uh<00:02:31.400> anything<00:02:31.879> in
can be shaved to be uh anything in
can be shaved to be uh anything in
between<00:02:32.560> because<00:02:33.280> it's<00:02:33.599> it's<00:02:33.720> a<00:02:34.200> mechanical
between because it's it's a mechanical
between because it's it's a mechanical
uh<00:02:35.400> Force<00:02:36.000> basically<00:02:36.400> it's<00:02:36.480> a<00:02:36.680> force<00:02:37.120> acting
uh Force basically it's a force acting
uh Force basically it's a force acting
on<00:02:37.959> a<00:02:38.120> tissue<00:02:38.519> that<00:02:38.640> it<00:02:38.920> transverses<00:02:39.920> so<00:02:40.080> you
on a tissue that it transverses so you
on a tissue that it transverses so you
can<00:02:40.360> change<00:02:40.720> the<00:02:40.879> intensity<00:02:41.519> the<00:02:41.720> frequency
can change the intensity the frequency
can change the intensity the frequency
the<00:02:43.120> duration<00:02:44.120> the<00:02:44.319> pulse<00:02:44.720> shape<00:02:45.200> of<00:02:45.319> the
the duration the pulse shape of the
the duration the pulse shape of the
ultrasound<00:02:46.120> to<00:02:46.280> create<00:02:46.640> anything<00:02:47.040> from<00:02:47.239> an
ultrasound to create anything from an
ultrasound to create anything from an
airbrush<00:02:48.519> you<00:02:48.680> know<00:02:48.840> to<00:02:49.000> a<00:02:49.319> hammer<00:02:50.319> okay<00:02:50.760> and<00:02:50.920> I
airbrush you know to a hammer okay and I
airbrush you know to a hammer okay and I
going<00:02:51.360> to<00:02:51.519> show<00:02:51.800> you<00:02:52.239> multiple<00:02:53.120> application
going to show you multiple application
going to show you multiple application
in<00:02:54.120> the<00:02:54.280> medical<00:02:54.680> field<00:02:55.440> that<00:02:55.599> can<00:02:55.800> be<00:02:56.400> enabled
in the medical field that can be enabled
in the medical field that can be enabled
just<00:02:57.640> by<00:02:57.959> focusing<00:02:58.959> physically<00:02:59.440> focusing
just by focusing physically focusing
just by focusing physically focusing
okay<00:03:02.080> so<00:03:02.760> this<00:03:03.000> idea<00:03:03.560> of<00:03:03.799> harnessing<00:03:04.400> focused
okay so this idea of harnessing focused
okay so this idea of harnessing focused
ultrasound<00:03:05.840> to<00:03:06.040> treat<00:03:06.319> lesions<00:03:06.799> in<00:03:06.959> the<00:03:07.120> brain
ultrasound to treat lesions in the brain
ultrasound to treat lesions in the brain
is<00:03:08.080> not<00:03:08.280> new<00:03:08.560> at<00:03:08.680> all<00:03:09.040> it's<00:03:09.239> when<00:03:09.440> I<00:03:09.560> was<00:03:09.799> born
is not new at all it's when I was born
is not new at all it's when I was born
this<00:03:10.480> idea<00:03:10.799> was<00:03:11.000> already<00:03:11.440> conceived<00:03:12.440> by
this idea was already conceived by
this idea was already conceived by
Pioneers<00:03:13.319> such<00:03:13.519> as<00:03:13.680> the<00:03:13.799> fry<00:03:14.280> brother<00:03:15.280> and
Pioneers such as the fry brother and
Pioneers such as the fry brother and
large<00:03:16.000> lexel<00:03:17.000> who<00:03:17.159> is<00:03:17.560> known<00:03:18.159> actually<00:03:18.519> as<00:03:18.680> the
large lexel who is known actually as the
large lexel who is known actually as the
inventor<00:03:19.360> of<00:03:19.480> the<00:03:19.599> gamma<00:03:19.959> knife<00:03:20.519> but<00:03:21.120> you<00:03:21.280> may
inventor of the gamma knife but you may
inventor of the gamma knife but you may
not<00:03:21.760> know<00:03:22.640> that<00:03:22.959> he<00:03:23.200> tried<00:03:23.799> to<00:03:23.920> perform
not know that he tried to perform
not know that he tried to perform
lobotomies<00:03:24.879> in<00:03:25.000> the<00:03:25.159> brain<00:03:25.440> non
lobotomies in the brain non
lobotomies in the brain non
invasively<00:03:27.400> uh<00:03:27.760> with<00:03:27.959> focused<00:03:28.400> ultrasound<00:03:29.200> in
invasively uh with focused ultrasound in
invasively uh with focused ultrasound in
the<00:03:29.439> 50<00:03:29.879> is<00:03:30.120> he<00:03:30.280> failed<00:03:31.239> so<00:03:31.439> he<00:03:31.599> then<00:03:31.799> invented
the 50 is he failed so he then invented
the 50 is he failed so he then invented
the<00:03:32.319> gamma
the gamma
the gamma
knife<00:03:34.360> and<00:03:34.599> it<00:03:34.760> makes<00:03:34.959> you<00:03:35.200> Ponder<00:03:35.760> you<00:03:36.159> know
knife and it makes you Ponder you know
knife and it makes you Ponder you know
why<00:03:37.599> why<00:03:38.280> those<00:03:38.760> Pioneers<00:03:39.720> fail<00:03:40.720> and<00:03:40.879> there
why why those Pioneers fail and there
why why those Pioneers fail and there
was<00:03:41.200> something<00:03:41.959> fundamental<00:03:42.959> that<00:03:43.120> they<00:03:43.200> were
was something fundamental that they were
was something fundamental that they were
missing<00:03:44.480> they<00:03:44.599> were<00:03:44.799> missing<00:03:45.200> the<00:03:45.400> vision<00:03:46.400> it
missing they were missing the vision it
missing they were missing the vision it
wasn't<00:03:47.000> until<00:03:47.799> the<00:03:47.959> invention<00:03:48.439> of<00:03:48.599> the<00:03:48.760> Mr<00:03:49.519> and
wasn't until the invention of the Mr and
wasn't until the invention of the Mr and
really<00:03:50.560> the<00:03:50.760> integration<00:03:51.360> of<00:03:51.560> Mr<00:03:52.519> with<00:03:52.720> Focus
really the integration of Mr with Focus
really the integration of Mr with Focus
ultrasound<00:03:54.239> that<00:03:54.439> we<00:03:54.680> could<00:03:55.159> get<00:03:55.560> the
ultrasound that we could get the
ultrasound that we could get the
feedback<00:03:56.959> both<00:03:57.200> the<00:03:57.640> anatomical<00:03:58.640> and<00:03:58.879> the
feedback both the anatomical and the
feedback both the anatomical and the
physiological
physiological
physiological
in<00:04:00.599> order<00:04:00.920> to<00:04:01.120> have<00:04:01.319> a<00:04:01.480> completely
in order to have a completely
in order to have a completely
non-invasive<00:04:02.879> closed<00:04:03.319> loop<00:04:04.159> surgical
non-invasive closed loop surgical
non-invasive closed loop surgical
procedure<00:04:06.360> okay<00:04:07.159> so<00:04:07.599> this<00:04:07.760> is<00:04:07.959> how<00:04:08.159> it<00:04:08.280> looks
procedure okay so this is how it looks
procedure okay so this is how it looks
you<00:04:09.000> know<00:04:09.280> the<00:04:09.439> operating<00:04:09.840> room<00:04:10.079> of<00:04:10.239> the
you know the operating room of the
you know the operating room of the
future<00:04:11.200> today<00:04:12.079> okay<00:04:12.280> this<00:04:12.400> is<00:04:12.519> an<00:04:12.680> MR<00:04:13.040> Suite
future today okay this is an MR Suite
future today okay this is an MR Suite
with<00:04:13.720> a<00:04:13.840> focused<00:04:14.159> ultrasound<00:04:14.760> system<00:04:15.680> and
with a focused ultrasound system and
with a focused ultrasound system and
I'll<00:04:16.079> give<00:04:16.359> several<00:04:16.720> examples<00:04:17.160> so<00:04:17.320> the<00:04:17.479> first
I'll give several examples so the first
I'll give several examples so the first
one<00:04:17.880> is<00:04:18.000> in<00:04:18.120> the<00:04:18.280> brain<00:04:19.079> one<00:04:19.280> of<00:04:19.639> the
one is in the brain one of the
one is in the brain one of the
neurological<00:04:20.880> conditions<00:04:21.239> that<00:04:21.400> can<00:04:21.560> be
neurological conditions that can be
neurological conditions that can be
treated<00:04:22.040> with<00:04:22.199> Focus<00:04:22.880> ultrasound<00:04:23.880> are
treated with Focus ultrasound are
treated with Focus ultrasound are
movement<00:04:24.800> disorders<00:04:25.639> like<00:04:25.960> Parkinson<00:04:26.800> or
movement disorders like Parkinson or
movement disorders like Parkinson or
essential<00:04:27.600> tremor<00:04:28.600> what<00:04:28.759> is<00:04:29.000> typical<00:04:30.000> to
essential tremor what is typical to
essential tremor what is typical to
those<00:04:31.160> conditions<00:04:32.160> uh<00:04:32.320> for<00:04:32.560> essential<00:04:32.960> tremor
those conditions uh for essential tremor
those conditions uh for essential tremor
for<00:04:33.800> example<00:04:34.800> is<00:04:35.560> uh
for example is uh
for example is uh
inability<00:04:37.680> to<00:04:38.360> uh<00:04:39.280> drink<00:04:40.280> or<00:04:40.479> eat<00:04:40.800> cereal<00:04:41.280> or
inability to uh drink or eat cereal or
inability to uh drink or eat cereal or
soup<00:04:41.919> without<00:04:42.199> spilling<00:04:42.720> everything<00:04:43.120> all
soup without spilling everything all
soup without spilling everything all
over<00:04:43.520> you<00:04:44.400> or<00:04:44.600> write<00:04:44.960> legibly<00:04:45.680> so<00:04:45.919> people<00:04:46.160> can
over you or write legibly so people can
over you or write legibly so people can
understand<00:04:46.919> it<00:04:47.759> and<00:04:47.919> be<00:04:48.280> really<00:04:48.600> independent
understand it and be really independent
understand it and be really independent
in<00:04:49.360> your<00:04:49.600> life<00:04:50.560> uh<00:04:50.720> without<00:04:51.160> the<00:04:51.479> the<00:04:51.639> help<00:04:51.919> of
in your life uh without the the help of
in your life uh without the the help of
others<00:04:53.039> so<00:04:53.199> I'd<00:04:53.360> like<00:04:53.520> you<00:04:53.639> to<00:04:53.800> meet<00:04:54.919> John<00:04:55.919> John
others so I'd like you to meet John John
others so I'd like you to meet John John
is<00:04:56.360> a<00:04:56.560> retired<00:04:57.039> professor<00:04:57.440> of<00:04:57.639> history<00:04:58.039> from
is a retired professor of history from
is a retired professor of history from
Virginia<00:04:59.759> so<00:04:59.919> he<00:05:00.120> suffered<00:05:00.520> from<00:05:00.840> essential
Virginia so he suffered from essential
Virginia so he suffered from essential
tremor<00:05:01.680> for<00:05:01.919> many<00:05:02.520> years<00:05:03.520> and<00:05:04.199> uh<00:05:04.440> medication
tremor for many years and uh medication
tremor for many years and uh medication
didn't<00:05:05.280> help<00:05:05.520> him<00:05:05.720> anymore<00:05:06.560> and<00:05:06.880> and<00:05:07.199> many<00:05:07.400> of
didn't help him anymore and and many of
didn't help him anymore and and many of
those<00:05:07.919> patients<00:05:08.320> refused<00:05:08.720> to<00:05:08.840> undergo
those patients refused to undergo
those patients refused to undergo
surgery<00:05:09.880> to<00:05:10.080> have<00:05:10.320> people<00:05:10.600> cut<00:05:10.880> into<00:05:11.080> their
surgery to have people cut into their
surgery to have people cut into their
brain<00:05:12.120> and<00:05:12.479> about<00:05:12.759> four<00:05:12.960> or<00:05:13.160> five<00:05:13.400> months<00:05:14.000> ago
brain and about four or five months ago
brain and about four or five months ago
he<00:05:16.039> uh<00:05:17.039> underwent<00:05:18.039> an<00:05:18.280> experimental
he uh underwent an experimental
he uh underwent an experimental
procedure<00:05:19.680> it<00:05:19.960> it<00:05:20.080> is<00:05:20.240> approved<00:05:20.800> under<00:05:21.800> an<00:05:21.960> FDA
procedure it it is approved under an FDA
procedure it it is approved under an FDA
Ide<00:05:23.280> at<00:05:23.400> the<00:05:23.479> University<00:05:24.400> of<00:05:24.680> Virginia<00:05:25.199> in
Ide at the University of Virginia in
Ide at the University of Virginia in
Charlottesville<00:05:26.759> using<00:05:27.120> focused<00:05:27.560> ultrasound
Charlottesville using focused ultrasound
Charlottesville using focused ultrasound
to<00:05:28.759> ablate<00:05:29.840> a<00:05:30.080> point<00:05:30.960> in<00:05:31.160> his<00:05:31.759> Talus<00:05:33.160> okay<00:05:34.160> and
to ablate a point in his Talus okay and
to ablate a point in his Talus okay and
this<00:05:34.720> is<00:05:34.880> his
this is his
this is his
handwriting<00:05:37.039> on<00:05:37.319> June<00:05:38.199> 20th<00:05:39.120> if<00:05:39.240> you<00:05:39.360> can<00:05:39.560> read
handwriting on June 20th if you can read
handwriting on June 20th if you can read
it
it
it
2011<00:05:42.680> okay<00:05:43.680> this<00:05:43.800> is<00:05:44.160> handwriting<00:05:44.720> in<00:05:44.880> the
2011 okay this is handwriting in the
2011 okay this is handwriting in the
morning<00:05:45.759> of<00:05:45.880> the<00:05:46.039> treatment<00:05:47.000> before<00:05:47.360> going
morning of the treatment before going
morning of the treatment before going
into<00:05:48.120> DMR<00:05:49.120> so<00:05:49.360> now<00:05:49.560> I'll<00:05:49.800> take<00:05:49.960> you<00:05:50.160> through
into DMR so now I'll take you through
into DMR so now I'll take you through
how<00:05:51.039> a<00:05:51.199> typical<00:05:51.639> procedure<00:05:52.160> like<00:05:52.360> that<00:05:52.560> looks
how a typical procedure like that looks
how a typical procedure like that looks
like<00:05:53.120> how<00:05:53.319> noninvasive<00:05:54.080> surgery<00:05:54.600> looks<00:05:55.319> looks
like how noninvasive surgery looks looks
like how noninvasive surgery looks looks
like<00:05:57.720> so<00:05:57.880> we<00:05:58.039> put<00:05:58.199> the<00:05:58.319> patient<00:05:58.600> on<00:05:58.759> the<00:05:58.919> Mr
like so we put the patient on the Mr
like so we put the patient on the Mr
table<00:05:59.759> we<00:05:59.880> attach<00:06:00.160> a<00:06:00.280> transducer<00:06:00.880> in<00:06:01.000> this
table we attach a transducer in this
table we attach a transducer in this
case<00:06:01.360> to<00:06:01.479> the<00:06:01.600> brain<00:06:01.960> but<00:06:02.120> if<00:06:02.240> it<00:06:02.360> will<00:06:02.520> be<00:06:02.680> a
case to the brain but if it will be a
case to the brain but if it will be a
different<00:06:03.160> organ<00:06:03.560> it<00:06:03.680> will<00:06:03.840> be<00:06:03.960> a<00:06:04.120> different
different organ it will be a different
different organ it will be a different
transducer<00:06:05.479> attached<00:06:05.880> to<00:06:06.080> the<00:06:06.440> uh<00:06:07.199> patient
transducer attached to the uh patient
transducer attached to the uh patient
and<00:06:08.639> the<00:06:08.840> physician<00:06:09.360> will<00:06:09.720> then<00:06:10.039> take<00:06:10.880> a
and the physician will then take a
and the physician will then take a
regular<00:06:11.520> Mr<00:06:12.000> scan<00:06:13.000> okay<00:06:14.000> and<00:06:14.720> the<00:06:14.960> objective
regular Mr scan okay and the objective
regular Mr scan okay and the objective
of<00:06:15.599> that<00:06:16.199> I<00:06:16.280> don't<00:06:16.479> have<00:06:16.599> a<00:06:16.759> pointer<00:06:17.240> here<00:06:17.479> but
of that I don't have a pointer here but
of that I don't have a pointer here but
you<00:06:17.720> see<00:06:18.000> the<00:06:18.599> green<00:06:19.160> sort<00:06:19.400> of<00:06:19.639> rectangle<00:06:20.199> or
you see the green sort of rectangle or
you see the green sort of rectangle or
trapez<00:06:21.639> this<00:06:21.800> is<00:06:22.000> a<00:06:22.160> sort<00:06:22.360> of<00:06:22.479> a<00:06:22.639> general<00:06:23.039> area
trapez this is a sort of a general area
trapez this is a sort of a general area
of<00:06:23.400> the<00:06:23.599> treatment<00:06:24.440> it's<00:06:24.560> a<00:06:24.800> safety<00:06:25.199> boundary
of the treatment it's a safety boundary
of the treatment it's a safety boundary
around<00:06:26.759> the<00:06:26.960> target<00:06:27.440> it's<00:06:27.560> a<00:06:27.759> Target<00:06:28.039> in<00:06:28.160> the
around the target it's a Target in the
around the target it's a Target in the
talus<00:06:29.039> okay<00:06:29.639> so<00:06:29.880> once<00:06:30.280> those<00:06:30.599> pictures<00:06:31.080> are
talus okay so once those pictures are
talus okay so once those pictures are
acquired<00:06:32.000> and<00:06:32.199> the<00:06:32.400> physician<00:06:33.400> has<00:06:33.599> drawn<00:06:34.039> you
acquired and the physician has drawn you
acquired and the physician has drawn you
know<00:06:34.319> all<00:06:34.479> the<00:06:34.720> necessary<00:06:35.599> safety<00:06:36.000> limits<00:06:36.319> and
know all the necessary safety limits and
know all the necessary safety limits and
so<00:06:36.720> on<00:06:37.720> he<00:06:37.919> selects<00:06:38.919> basically<00:06:39.639> a<00:06:39.840> point<00:06:40.039> you
so on he selects basically a point you
so on he selects basically a point you
see<00:06:40.360> the<00:06:40.479> round<00:06:40.840> point<00:06:41.080> in<00:06:41.199> the<00:06:41.319> Middle<00:06:41.599> where
see the round point in the Middle where
see the round point in the Middle where
the<00:06:41.880> caror<00:06:42.440> is<00:06:43.160> and<00:06:43.280> he<00:06:43.440> presses<00:06:43.919> this<00:06:44.080> blue
the caror is and he presses this blue
the caror is and he presses this blue
button<00:06:44.759> called<00:06:45.000> sonicate<00:06:45.720> we<00:06:45.840> call<00:06:46.599> this
button called sonicate we call this
button called sonicate we call this
instance<00:06:48.000> of<00:06:48.520> injecting<00:06:49.000> the<00:06:49.160> energy<00:06:49.520> we<00:06:49.680> call
instance of injecting the energy we call
instance of injecting the energy we call
it<00:06:50.160> sonication<00:06:51.160> the<00:06:51.280> only<00:06:51.599> hand<00:06:51.880> workk<00:06:52.440> The
it sonication the only hand workk The
it sonication the only hand workk The
Physician<00:06:53.039> does<00:06:53.360> here<00:06:53.800> is<00:06:53.960> moving<00:06:54.280> a<00:06:54.479> mouse
Physician does here is moving a mouse
Physician does here is moving a mouse
this<00:06:55.080> is<00:06:55.240> the<00:06:55.360> only<00:06:56.039> device<00:06:56.400> in<00:06:56.560> it<00:06:56.800> in<00:06:56.960> this
this is the only device in it in this
this is the only device in it in this
treatment<00:06:58.599> so<00:06:59.000> he<00:06:59.160> presses<00:06:59.879> sonicate<00:07:00.879> and
treatment so he presses sonicate and
treatment so he presses sonicate and
this<00:07:01.160> is<00:07:01.360> what<00:07:01.560> happens<00:07:01.879> you<00:07:02.000> see<00:07:02.160> the
this is what happens you see the
this is what happens you see the
transducer<00:07:02.840> the<00:07:02.960> light<00:07:03.240> blue<00:07:03.960> there's<00:07:04.280> water
transducer the light blue there's water
transducer the light blue there's water
in<00:07:04.720> between<00:07:05.000> the<00:07:05.160> skull<00:07:05.440> and<00:07:05.560> the
in between the skull and the
in between the skull and the
transducer<00:07:07.240> and<00:07:07.360> it<00:07:07.599> does<00:07:07.960> this<00:07:08.360> burst<00:07:08.680> of
transducer and it does this burst of
transducer and it does this burst of
energy<00:07:09.440> it<00:07:09.599> elevates<00:07:10.039> the<00:07:10.440> temperature<00:07:11.440> we
energy it elevates the temperature we
energy it elevates the temperature we
first<00:07:11.919> need<00:07:12.160> to<00:07:12.479> verify<00:07:13.240> that<00:07:13.400> we<00:07:13.520> are<00:07:13.680> on
first need to verify that we are on
first need to verify that we are on
target<00:07:14.560> right<00:07:15.199> so<00:07:15.440> the<00:07:15.599> first<00:07:16.000> sonication<00:07:17.000> is
target right so the first sonication is
target right so the first sonication is
at<00:07:17.400> low<00:07:17.800> energy<00:07:18.599> it<00:07:18.759> doesn't<00:07:19.319> do<00:07:19.639> any<00:07:20.039> damage
at low energy it doesn't do any damage
at low energy it doesn't do any damage
but<00:07:21.199> it<00:07:21.360> elevates<00:07:21.879> the<00:07:22.560> temperature<00:07:23.560> by<00:07:23.759> a<00:07:23.879> few
but it elevates the temperature by a few
but it elevates the temperature by a few
degrees<00:07:24.800> and<00:07:25.000> one<00:07:25.120> of<00:07:25.280> the<00:07:25.400> unique
degrees and one of the unique
degrees and one of the unique
capabilities<00:07:26.479> that<00:07:26.639> we<00:07:26.840> leverage<00:07:27.759> with<00:07:28.080> DMR
capabilities that we leverage with DMR
capabilities that we leverage with DMR
is<00:07:29.240> the<00:07:29.560> ability<00:07:29.879> to<00:07:30.000> measure<00:07:30.360> temperature
is the ability to measure temperature
is the ability to measure temperature
non<00:07:31.160> invasively<00:07:32.160> okay<00:07:32.360> this<00:07:32.440> is<00:07:32.639> really<00:07:32.800> a
non invasively okay this is really a
non invasively okay this is really a
unique<00:07:33.560> capability<00:07:34.560> uh<00:07:34.680> of<00:07:34.879> DMR<00:07:35.440> it's<00:07:35.639> not<00:07:36.440> it
unique capability uh of DMR it's not it
unique capability uh of DMR it's not it
is<00:07:36.680> not<00:07:36.840> being<00:07:37.039> used<00:07:37.360> in<00:07:37.599> in<00:07:37.960> regular
is not being used in in regular
is not being used in in regular
Diagnostic<00:07:39.000> Imaging<00:07:40.000> but<00:07:40.280> here<00:07:40.759> we<00:07:40.879> can<00:07:41.120> get
Diagnostic Imaging but here we can get
Diagnostic Imaging but here we can get
both<00:07:41.840> the<00:07:42.000> anatomical<00:07:42.599> Imaging<00:07:43.160> and<00:07:43.319> the
both the anatomical Imaging and the
both the anatomical Imaging and the
temperature<00:07:44.000> maps<00:07:44.599> in<00:07:44.759> real<00:07:45.039> time<00:07:45.280> and<00:07:45.479> you
temperature maps in real time and you
temperature maps in real time and you
can<00:07:45.680> see<00:07:45.919> the<00:07:46.080> points<00:07:46.440> there<00:07:46.599> on<00:07:46.720> the<00:07:46.919> graph
can see the points there on the graph
can see the points there on the graph
the<00:07:47.919> temperature<00:07:48.319> was<00:07:48.520> raised<00:07:48.840> to<00:07:49.120> 43°
the temperature was raised to 43°
the temperature was raised to 43°
temporarily<00:07:51.360> this<00:07:51.520> doesn't<00:07:51.800> cause<00:07:52.080> any
temporarily this doesn't cause any
temporarily this doesn't cause any
damage<00:07:53.000> but<00:07:53.159> the<00:07:53.319> point<00:07:53.680> is<00:07:54.000> we<00:07:54.120> are<00:07:54.360> right<00:07:54.560> on
damage but the point is we are right on
damage but the point is we are right on
target<00:07:55.720> so<00:07:56.000> once<00:07:56.800> the<00:07:57.000> physician<00:07:57.680> verifies
target so once the physician verifies
target so once the physician verifies
that<00:07:58.840> the<00:07:58.960> focal<00:07:59.599> spot<00:08:00.000> is<00:08:00.159> on<00:08:00.360> the<00:08:00.520> Target
that the focal spot is on the Target
that the focal spot is on the Target
that<00:08:01.120> he<00:08:01.240> has<00:08:01.440> chosen<00:08:02.440> then<00:08:02.599> we<00:08:02.759> can<00:08:02.919> move<00:08:03.639> to
that he has chosen then we can move to
that he has chosen then we can move to
perform<00:08:04.440> you<00:08:04.520> know<00:08:04.680> a<00:08:04.800> full<00:08:05.479> energy<00:08:06.479> uh
perform you know a full energy uh
perform you know a full energy uh
ablation<00:08:08.080> like<00:08:08.240> you<00:08:08.360> see<00:08:08.680> here<00:08:09.039> and<00:08:09.159> you<00:08:09.240> see
ablation like you see here and you see
ablation like you see here and you see
the<00:08:09.639> temperature<00:08:10.479> rises<00:08:10.960> to<00:08:11.199> like<00:08:11.599> 55<00:08:12.159> to
the temperature rises to like 55 to
the temperature rises to like 55 to
60°<00:08:14.000> if<00:08:14.120> you<00:08:14.240> do<00:08:14.440> it<00:08:14.560> for<00:08:14.759> more<00:08:14.960> than<00:08:15.080> a<00:08:15.199> second
60° if you do it for more than a second
60° if you do it for more than a second
it's<00:08:15.720> enough<00:08:16.039> to<00:08:16.560> basically<00:08:17.479> uh<00:08:18.479> uh<00:08:18.680> destroy
it's enough to basically uh uh destroy
it's enough to basically uh uh destroy
the<00:08:19.759> uh<00:08:19.919> proteins<00:08:20.440> the
the uh proteins the
the uh proteins the
cells<00:08:22.680> this<00:08:22.800> is<00:08:22.960> the<00:08:23.080> outcome<00:08:23.520> from<00:08:23.639> a<00:08:23.800> patient
cells this is the outcome from a patient
cells this is the outcome from a patient
perspective<00:08:25.080> same<00:08:25.479> day<00:08:25.759> after<00:08:26.080> this
perspective same day after this
perspective same day after this
treatment<00:08:27.240> okay<00:08:27.560> this<00:08:27.680> is<00:08:27.800> an<00:08:28.199> immediate<00:08:29.199> Rel
treatment okay this is an immediate Rel
treatment okay this is an immediate Rel
and
immed<00:08:36.719> John<00:08:37.080> is<00:08:37.200> one<00:08:37.519> of<00:08:37.839> of<00:08:38.159> like
immed John is one of of like
immed John is one of of like
dozen<00:08:40.279> very<00:08:41.159> uh<00:08:41.479> heroic<00:08:42.240> courageous<00:08:42.880> people
dozen very uh heroic courageous people
dozen very uh heroic courageous people
who<00:08:43.800> volunteer<00:08:44.399> for<00:08:44.720> the<00:08:44.880> study<00:08:45.320> and<00:08:45.519> you<00:08:45.760> have
who volunteer for the study and you have
who volunteer for the study and you have
to<00:08:46.880> understand<00:08:47.200> you<00:08:47.320> know<00:08:47.800> what<00:08:47.959> is<00:08:48.640> in
to understand you know what is in
to understand you know what is in
people's<00:08:49.279> mind<00:08:49.720> when<00:08:50.120> when<00:08:50.279> they<00:08:50.440> are<00:08:50.600> willing
people's mind when when they are willing
people's mind when when they are willing
to<00:08:51.600> take<00:08:51.800> the<00:08:52.200> risk<00:08:53.200> and<00:08:53.680> this<00:08:53.760> is<00:08:54.120> quote<00:08:54.440> from
to take the risk and this is quote from
to take the risk and this is quote from
John<00:08:55.160> after<00:08:55.440> he<00:08:55.680> wrote<00:08:56.000> it<00:08:56.200> he<00:08:56.320> said
John after he wrote it he said
John after he wrote it he said
miraculous<00:08:57.640> and<00:08:57.839> his<00:08:58.120> wife<00:08:58.839> said<00:08:59.160> this<00:08:59.279> is<00:08:59.480> is
miraculous and his wife said this is is
miraculous and his wife said this is is
the<00:08:59.720> happiest<00:09:00.240> moment<00:09:00.880> of<00:09:01.120> my<00:09:01.440> life<00:09:02.440> and<00:09:02.560> you
the happiest moment of my life and you
the happiest moment of my life and you
wonder<00:09:03.120> why<00:09:03.399> I<00:09:03.480> mean<00:09:04.399> one<00:09:04.560> of<00:09:04.760> the<00:09:05.079> messages
wonder why I mean one of the messages
wonder why I mean one of the messages
I'd<00:09:05.800> like<00:09:05.959> to<00:09:06.120> carry<00:09:06.440> over<00:09:07.120> is<00:09:07.440> what<00:09:07.640> about
I'd like to carry over is what about
I'd like to carry over is what about
defending<00:09:08.560> quality<00:09:08.959> of<00:09:09.200> life<00:09:09.560> I<00:09:09.600> mean<00:09:09.800> those
defending quality of life I mean those
defending quality of life I mean those
people<00:09:10.279> lose<00:09:10.519> their<00:09:10.720> independence<00:09:11.560> they<00:09:11.959> are
people lose their independence they are
people lose their independence they are
dependent<00:09:12.959> on<00:09:13.279> others<00:09:14.279> and<00:09:14.519> and<00:09:14.640> John<00:09:14.959> today
dependent on others and and John today
dependent on others and and John today
is<00:09:15.720> fully<00:09:16.079> independent<00:09:17.000> he<00:09:17.360> returned<00:09:17.680> to
is fully independent he returned to
is fully independent he returned to
normal<00:09:18.880> life<00:09:19.320> routine<00:09:20.320> and<00:09:20.480> he's<00:09:20.720> also<00:09:21.000> play
normal life routine and he's also play
normal life routine and he's also play
golf<00:09:21.880> like<00:09:22.040> you<00:09:22.200> do<00:09:22.440> in<00:09:22.640> in<00:09:22.800> Virginia<00:09:23.600> right
golf like you do in in Virginia right
golf like you do in in Virginia right
when<00:09:24.160> you
when you
when you
are<00:09:25.880> you<00:09:26.160> know
are you know
are you know
retired<00:09:29.120> okay
retired okay
retired okay
so<00:09:30.399> you<00:09:30.519> can<00:09:30.720> see<00:09:31.200> here<00:09:32.200> the<00:09:32.399> spot<00:09:32.800> it's<00:09:33.000> like<00:09:33.160> 3
so you can see here the spot it's like 3
so you can see here the spot it's like 3
mm<00:09:34.000> in<00:09:34.120> the<00:09:34.240> middle<00:09:34.480> of<00:09:34.560> the<00:09:34.680> brain<00:09:35.000> there's<00:09:35.240> no
mm in the middle of the brain there's no
mm in the middle of the brain there's no
damage<00:09:36.240> outside<00:09:37.079> is<00:09:37.360> suffers<00:09:37.680> from<00:09:37.880> no<00:09:38.399> neural
damage outside is suffers from no neural
damage outside is suffers from no neural
deficit<00:09:40.360> there's<00:09:40.600> no<00:09:40.880> recovery<00:09:41.440> needed<00:09:41.959> no
deficit there's no recovery needed no
deficit there's no recovery needed no
nothing<00:09:42.880> he's<00:09:43.160> back<00:09:43.360> to<00:09:43.480> his<00:09:43.640> normal<00:09:44.040> life
nothing he's back to his normal life
nothing he's back to his normal life
let's<00:09:45.000> move<00:09:45.560> now<00:09:46.560> to<00:09:46.720> a<00:09:46.880> more<00:09:47.120> painful
let's move now to a more painful
let's move now to a more painful
subject<00:09:49.240> pain<00:09:49.839> is<00:09:50.040> something<00:09:50.480> that<00:09:50.800> can<00:09:50.959> make
subject pain is something that can make
subject pain is something that can make
your<00:09:51.399> life<00:09:51.839> miserable<00:09:52.839> and<00:09:53.000> people<00:09:53.200> are
your life miserable and people are
your life miserable and people are
suffering<00:09:53.920> from<00:09:54.120> all<00:09:54.360> kinds<00:09:54.560> of<00:09:54.800> pain<00:09:55.160> like
suffering from all kinds of pain like
suffering from all kinds of pain like
neuropathic<00:09:56.480> pain<00:09:56.720> lower<00:09:57.120> back<00:09:57.839> pain<00:09:58.839> and
neuropathic pain lower back pain and
neuropathic pain lower back pain and
cancer<00:10:00.279> pain<00:10:00.640> from<00:10:01.200> bone<00:10:01.480> metastasis<00:10:02.320> when<00:10:02.519> it
cancer pain from bone metastasis when it
cancer pain from bone metastasis when it
you<00:10:02.880> know<00:10:03.120> the<00:10:03.440> metastasis<00:10:04.440> get<00:10:04.640> to<00:10:04.800> your<00:10:04.959> bin
you know the metastasis get to your bin
you know the metastasis get to your bin
sometimes<00:10:05.839> they<00:10:05.959> are<00:10:06.839> uh<00:10:07.000> very<00:10:07.360> painful<00:10:07.920> all
sometimes they are uh very painful all
sometimes they are uh very painful all
those<00:10:08.399> indication<00:10:09.000> have<00:10:09.240> already<00:10:10.279> been<00:10:11.279> shown
those indication have already been shown
those indication have already been shown
uh<00:10:12.399> to<00:10:12.560> be<00:10:12.760> successfully<00:10:13.320> treated<00:10:13.880> by<00:10:14.640> uh
uh to be successfully treated by uh
uh to be successfully treated by uh
Focus<00:10:15.440> ultrasound<00:10:16.360> relieving<00:10:16.880> the<00:10:17.040> pain
Focus ultrasound relieving the pain
Focus ultrasound relieving the pain
again<00:10:18.360> very<00:10:18.760> fast<00:10:19.760> and<00:10:20.200> I<00:10:20.279> would<00:10:20.440> like<00:10:20.600> to<00:10:20.760> tell
again very fast and I would like to tell
again very fast and I would like to tell
you<00:10:21.839> about<00:10:23.000> um
you about um
you about um
PJ<00:10:25.800> uh<00:10:26.360> he's<00:10:26.600> a<00:10:26.839> 78<00:10:27.640> years<00:10:28.399> um<00:10:28.760> farmer
PJ uh he's a 78 years um farmer
PJ uh he's a 78 years um farmer
who<00:10:30.640> suffered<00:10:31.200> from<00:10:32.040> how<00:10:32.160> should<00:10:32.399> I<00:10:32.560> say<00:10:32.920> it's
who suffered from how should I say it's
who suffered from how should I say it's
called<00:10:33.360> pain<00:10:33.600> in<00:10:33.720> the<00:10:33.880> butt<00:10:34.240> he<00:10:34.399> had<00:10:34.560> a
called pain in the butt he had a
called pain in the butt he had a
metastasis<00:10:36.120> in<00:10:36.279> his<00:10:36.519> right<00:10:36.760> but<00:10:37.760> but<00:10:38.399> and<00:10:38.639> and
metastasis in his right but but and and
metastasis in his right but but and and
he<00:10:38.959> couldn't<00:10:39.240> see<00:10:39.839> even<00:10:40.120> with<00:10:40.720> medication<00:10:41.720> he
he couldn't see even with medication he
he couldn't see even with medication he
had<00:10:42.000> to<00:10:42.160> forgo<00:10:42.639> you<00:10:42.760> know<00:10:42.959> about<00:10:43.240> all<00:10:43.360> the
had to forgo you know about all the
had to forgo you know about all the
farmer<00:10:44.240> uh<00:10:44.360> Farm
farmer uh Farm
farmer uh Farm
activities<00:10:47.480> uh<00:10:48.480> he<00:10:48.639> was<00:10:49.079> uh<00:10:49.240> treated<00:10:49.680> with
activities uh he was uh treated with
activities uh he was uh treated with
radiation<00:10:50.560> therapy<00:10:51.079> state-of-the-art
radiation therapy state-of-the-art
radiation therapy state-of-the-art
radiation<00:10:52.480> therapy<00:10:53.079> but<00:10:53.360> it<00:10:53.480> didn't<00:10:53.760> help
radiation therapy but it didn't help
radiation therapy but it didn't help
many<00:10:54.440> patients<00:10:54.880> like<00:10:55.120> that<00:10:55.480> failed<00:10:55.920> radiation
many patients like that failed radiation
many patients like that failed radiation
therapy<00:10:58.279> and<00:10:58.720> again<00:10:59.040> he<00:10:59.440> volunteered<00:11:00.000> to<00:11:00.160> a
therapy and again he volunteered to a
therapy and again he volunteered to a
pivotal<00:11:01.000> study<00:11:02.000> uh<00:11:02.320> that<00:11:02.440> we<00:11:02.760> run<00:11:03.760> uh
pivotal study uh that we run uh
pivotal study uh that we run uh
worldwide<00:11:04.760> also<00:11:05.040> in<00:11:05.160> the
worldwide also in the
worldwide also in the
US<00:11:06.959> and
US and
US and
um<00:11:09.639> his<00:11:09.880> wife<00:11:10.600> actually<00:11:11.440> uh<00:11:11.560> took<00:11:11.839> him<00:11:12.440> they
um his wife actually uh took him they
um his wife actually uh took him they
drove<00:11:13.120> like<00:11:13.320> 3<00:11:13.600> hours<00:11:13.959> from<00:11:14.240> their<00:11:14.760> Farm<00:11:15.440> to
drove like 3 hours from their Farm to
drove like 3 hours from their Farm to
the<00:11:16.360> hospital<00:11:17.360> he<00:11:17.560> had<00:11:17.760> to<00:11:18.079> sit<00:11:18.399> on<00:11:18.560> a<00:11:18.880> on<00:11:19.000> a
the hospital he had to sit on a on a
the hospital he had to sit on a on a
cushion<00:11:20.279> stand<00:11:20.680> still<00:11:21.200> I<00:11:21.279> mean<00:11:21.480> not<00:11:21.639> to<00:11:21.760> move
cushion stand still I mean not to move
cushion stand still I mean not to move
because<00:11:22.320> it<00:11:22.440> was<00:11:22.639> very
because it was very
because it was very
painful<00:11:24.480> he<00:11:24.639> took<00:11:24.839> the
painful he took the
painful he took the
treatment<00:11:26.920> and<00:11:27.440> uh<00:11:27.639> on<00:11:27.839> the<00:11:28.040> way<00:11:28.639> uh<00:11:29.000> back
treatment and uh on the way uh back
treatment and uh on the way uh back
he<00:11:30.079> drove<00:11:30.399> the<00:11:30.600> car<00:11:30.920> the<00:11:31.079> truck<00:11:31.399> by
he drove the car the truck by
he drove the car the truck by
himself<00:11:33.720> so<00:11:34.040> again<00:11:34.480> this<00:11:34.639> is<00:11:34.959> an<00:11:35.120> immediate
himself so again this is an immediate
himself so again this is an immediate
relief<00:11:36.560> and<00:11:36.760> and<00:11:36.880> you<00:11:37.040> have<00:11:37.160> to<00:11:37.680> understand
relief and and you have to understand
relief and and you have to understand
what's<00:11:38.600> you<00:11:38.720> know<00:11:39.200> those<00:11:39.519> people<00:11:40.279> feel<00:11:40.839> and
what's you know those people feel and
what's you know those people feel and
what<00:11:41.160> their<00:11:41.880> family<00:11:42.880> uh<00:11:43.240> experience<00:11:43.920> when<00:11:44.079> it
what their family uh experience when it
what their family uh experience when it
happens<00:11:45.760> uh<00:11:46.040> he<00:11:47.000> returned<00:11:47.399> again<00:11:47.760> to<00:11:48.320> you<00:11:48.440> know
happens uh he returned again to you know
happens uh he returned again to you know
his<00:11:48.880> daily<00:11:49.160> routine<00:11:49.480> in<00:11:49.639> the<00:11:49.760> farm<00:11:50.079> and<00:11:50.279> rides
his daily routine in the farm and rides
his daily routine in the farm and rides
his<00:11:50.959> tractor<00:11:51.880> he<00:11:52.040> rides<00:11:52.320> his<00:11:52.480> horse<00:11:52.760> to<00:11:52.920> their
his tractor he rides his horse to their
his tractor he rides his horse to their
mountain<00:11:53.680> cabin<00:11:54.680> uh<00:11:55.240> regularly<00:11:56.240> and<00:11:56.880> uh<00:11:57.320> he
mountain cabin uh regularly and uh he
mountain cabin uh regularly and uh he
has<00:11:57.639> been<00:11:57.959> very<00:11:58.279> happy<00:11:59.639> but<00:11:59.880> now<00:12:00.519> you<00:12:00.720> asked<00:12:00.959> me
has been very happy but now you asked me
has been very happy but now you asked me
you<00:12:01.240> know<00:12:01.839> but<00:12:02.120> what<00:12:02.279> about<00:12:02.639> war<00:12:03.000> you<00:12:03.120> know<00:12:03.279> the
you know but what about war you know the
you know but what about war you know the
war<00:12:03.600> on<00:12:03.800> cancer<00:12:04.279> show<00:12:04.519> us<00:12:04.800> some<00:12:05.639> primary
war on cancer show us some primary
war on cancer show us some primary
cancer<00:12:06.720> what<00:12:06.880> can<00:12:07.000> be<00:12:07.240> done<00:12:07.560> there<00:12:08.560> so<00:12:08.760> I<00:12:08.880> have
cancer what can be done there so I have
cancer what can be done there so I have
good<00:12:09.200> news<00:12:09.399> and<00:12:09.600> bad<00:12:09.920> news<00:12:10.920> the<00:12:11.120> good<00:12:11.320> news
good news and bad news the good news
good news and bad news the good news
there's<00:12:12.079> a<00:12:12.240> lot<00:12:12.720> that<00:12:12.880> can<00:12:13.079> be<00:12:13.240> done<00:12:13.800> and<00:12:13.920> it
there's a lot that can be done and it
there's a lot that can be done and it
has<00:12:14.199> been<00:12:14.360> shown<00:12:14.839> actually<00:12:15.279> outside<00:12:15.680> of<00:12:15.880> the
has been shown actually outside of the
has been shown actually outside of the
US
US
US
and<00:12:19.360> doing<00:12:19.760> that<00:12:19.959> in<00:12:20.160> the<00:12:20.440> US<00:12:21.440> is<00:12:21.680> is<00:12:21.880> very
and doing that in the US is is very
and doing that in the US is is very
painful<00:12:22.639> I<00:12:22.720> mean<00:12:23.079> I<00:12:23.320> I<00:12:23.399> don't<00:12:23.600> see<00:12:24.079> without<00:12:24.680> you
painful I mean I I don't see without you
painful I mean I I don't see without you
know<00:12:25.079> this<00:12:25.600> nation<00:12:26.600> taking<00:12:27.040> it<00:12:27.279> as<00:12:27.440> a<00:12:27.760> as<00:12:27.920> a
know this nation taking it as a as a
know this nation taking it as a as a
something<00:12:28.839> collect<00:12:29.279> active<00:12:30.120> will<00:12:30.639> or
something collect active will or
something collect active will or
something<00:12:31.399> that<00:12:31.519> is<00:12:31.639> a<00:12:31.880> national<00:12:32.839> goal<00:12:33.199> to
something that is a national goal to
something that is a national goal to
make<00:12:33.639> that<00:12:33.880> happen<00:12:34.560> it<00:12:34.680> will<00:12:35.240> not<00:12:35.519> happen<00:12:35.880> and
make that happen it will not happen and
make that happen it will not happen and
it's<00:12:36.240> not<00:12:36.440> just<00:12:36.639> because<00:12:36.839> of<00:12:37.040> Regulation<00:12:38.040> it's
it's not just because of Regulation it's
it's not just because of Regulation it's
because<00:12:38.519> of<00:12:38.720> the<00:12:38.880> amount<00:12:39.639> of<00:12:39.839> money<00:12:40.279> needed
because of the amount of money needed
because of the amount of money needed
under<00:12:41.440> the<00:12:41.639> current<00:12:42.519> you<00:12:42.639> know
under the current you know
under the current you know
evidence-based<00:12:43.800> medicine<00:12:44.320> and<00:12:44.480> the<00:12:44.600> size<00:12:44.839> of
evidence-based medicine and the size of
evidence-based medicine and the size of
Trials<00:12:45.480> and<00:12:45.639> so<00:12:45.880> on<00:12:46.880> uh<00:12:47.440> to<00:12:47.839> to<00:12:48.000> make<00:12:48.160> it<00:12:48.399> happen
Trials and so on uh to to make it happen
Trials and so on uh to to make it happen
so<00:12:49.320> the<00:12:49.440> first<00:12:49.639> two<00:12:50.079> applications<00:12:51.079> are<00:12:51.440> breast
so the first two applications are breast
so the first two applications are breast
cancer<00:12:52.120> and<00:12:52.399> prostate<00:12:52.839> cancer<00:12:53.440> they<00:12:53.560> were<00:12:53.800> the
cancer and prostate cancer they were the
cancer and prostate cancer they were the
first<00:12:54.320> to<00:12:54.480> be<00:12:54.639> treated<00:12:55.040> by<00:12:55.160> focused
first to be treated by focused
first to be treated by focused
ultrasound<00:12:57.040> and<00:12:57.800> uh<00:12:58.360> we<00:12:58.519> have<00:12:58.760> better<00:12:59.240> and
ultrasound and uh we have better and
ultrasound and uh we have better and
surgery<00:13:00.040> uh<00:13:00.199> results<00:13:00.600> in<00:13:00.800> breast<00:13:01.440> but<00:13:02.440> I<00:13:02.560> have
surgery uh results in breast but I have
surgery uh results in breast but I have
a<00:13:02.839> message<00:13:03.160> for<00:13:03.760> the<00:13:03.920> men<00:13:04.240> here<00:13:04.440> we<00:13:04.560> heard
a message for the men here we heard
a message for the men here we heard
yesterday<00:13:06.040> qen<00:13:07.040> uh<00:13:07.240> talking<00:13:07.560> about<00:13:08.519> the<00:13:08.959> uh
yesterday qen uh talking about the uh
yesterday qen uh talking about the uh
adverse<00:13:09.560> event<00:13:09.880> trait<00:13:10.240> in<00:13:10.440> prostate<00:13:10.920> cancer
adverse event trait in prostate cancer
adverse event trait in prostate cancer
there<00:13:12.079> is<00:13:12.320> a<00:13:12.480> unique<00:13:12.839> opportunity<00:13:13.399> now<00:13:13.680> with
there is a unique opportunity now with
there is a unique opportunity now with
focused<00:13:14.240> ultrasound<00:13:14.800> Guided<00:13:15.160> by
focused ultrasound Guided by
focused ultrasound Guided by
mrr<00:13:16.839> because<00:13:17.320> we<00:13:17.519> can<00:13:18.320> actually<00:13:18.760> think<00:13:19.199> about
mrr because we can actually think about
mrr because we can actually think about
prostate<00:13:20.720> lumpectomy<00:13:21.480> treating<00:13:22.120> just<00:13:22.600> the
prostate lumpectomy treating just the
prostate lumpectomy treating just the
focal<00:13:23.320> lesion<00:13:23.959> and<00:13:24.120> not<00:13:24.320> removing<00:13:24.760> the<00:13:24.880> whole
focal lesion and not removing the whole
focal lesion and not removing the whole
gland<00:13:26.160> and<00:13:26.399> by<00:13:26.680> that<00:13:27.120> avoiding<00:13:27.600> all<00:13:27.800> the
gland and by that avoiding all the
gland and by that avoiding all the
issues<00:13:28.440> with<00:13:29.120> potency<00:13:29.760> and<00:13:30.000> and
continents<00:13:33.360> well<00:13:34.160> there<00:13:34.279> are<00:13:34.560> other<00:13:35.519> uh<00:13:36.040> you
continents well there are other uh you
continents well there are other uh you
know<00:13:36.600> cancer<00:13:37.079> tumors<00:13:37.959> in<00:13:38.160> the<00:13:38.440> abdomen<00:13:39.160> quite
know cancer tumors in the abdomen quite
know cancer tumors in the abdomen quite
little<00:13:40.079> very<00:13:40.320> little<00:13:40.800> actually<00:13:41.240> pancreas
little very little actually pancreas
little very little actually pancreas
liver<00:13:43.120> kidney<00:13:44.120> the<00:13:44.279> challenge<00:13:45.320> there<00:13:46.320> with<00:13:46.880> a
liver kidney the challenge there with a
liver kidney the challenge there with a
breathing<00:13:47.600> and<00:13:47.839> awake<00:13:48.480> patient<00:13:49.199> and<00:13:49.320> in<00:13:49.480> all
breathing and awake patient and in all
breathing and awake patient and in all
our<00:13:49.880> treatment<00:13:50.399> the<00:13:50.680> patient<00:13:51.600> is<00:13:51.800> awake<00:13:52.199> and
our treatment the patient is awake and
our treatment the patient is awake and
conscious<00:13:53.160> and<00:13:53.360> he<00:13:53.519> speaks<00:13:53.920> with<00:13:54.120> the
conscious and he speaks with the
conscious and he speaks with the
physician<00:13:56.120> um<00:13:56.839> is<00:13:57.079> you<00:13:57.240> have<00:13:57.440> to<00:13:58.079> learn<00:13:58.519> uh
physician um is you have to learn uh
physician um is you have to learn uh
teach<00:13:59.199> mrr<00:13:59.480> some<00:13:59.720> tricks<00:14:00.120> how<00:14:00.279> to<00:14:01.000> uh<00:14:01.279> do<00:14:01.440> it<00:14:01.560> in
teach mrr some tricks how to uh do it in
teach mrr some tricks how to uh do it in
real<00:14:02.240> time<00:14:03.240> and<00:14:04.040> um<00:14:05.040> this<00:14:05.199> will<00:14:05.440> take<00:14:05.680> time
real time and um this will take time
real time and um this will take time
this<00:14:06.120> will<00:14:06.360> take<00:14:06.600> 2<00:14:06.839> years<00:14:07.199> but<00:14:07.320> I<00:14:07.440> have<00:14:07.600> now<00:14:07.759> a
this will take 2 years but I have now a
this will take 2 years but I have now a
message<00:14:08.279> to<00:14:08.440> the<00:14:08.800> ladies<00:14:09.800> and<00:14:10.000> this<00:14:10.199> is<00:14:11.040> uh<00:14:11.199> in
message to the ladies and this is uh in
message to the ladies and this is uh in
2004<00:14:12.959> the<00:14:13.199> FDA<00:14:14.199> has<00:14:14.399> approved<00:14:14.800> ided<00:14:15.360> Focus
2004 the FDA has approved ided Focus
2004 the FDA has approved ided Focus
ultrasound<00:14:16.279> for<00:14:16.440> the<00:14:16.560> treatment<00:14:17.040> of
ultrasound for the treatment of
ultrasound for the treatment of
symptomatic<00:14:18.320> uterine
symptomatic uterine
symptomatic uterine
fibroids<00:14:20.519> uh<00:14:20.920> women<00:14:21.920> suffers<00:14:22.399> from<00:14:22.839> that<00:14:23.839> uh
fibroids uh women suffers from that uh
fibroids uh women suffers from that uh
disease<00:14:24.920> or<00:14:25.199> those<00:14:25.440> tumors<00:14:26.079> have<00:14:26.639> uh<00:14:26.800> heavy
disease or those tumors have uh heavy
disease or those tumors have uh heavy
bleeding<00:14:27.440> during<00:14:27.880> period<00:14:28.720> abdom<00:14:29.279> Al<00:14:29.440> pressure
bleeding during period abdom Al pressure
bleeding during period abdom Al pressure
back<00:14:30.279> pain<00:14:31.000> frequent<00:14:31.480> urination<00:14:32.480> and
back pain frequent urination and
back pain frequent urination and
sometimes<00:14:33.600> that<00:14:33.839> can<00:14:34.279> they<00:14:34.880> cannot<00:14:35.240> even
sometimes that can they cannot even
sometimes that can they cannot even
conceive<00:14:36.000> and<00:14:36.240> become<00:14:36.600> pregnant<00:14:37.160> because<00:14:37.360> of
conceive and become pregnant because of
conceive and become pregnant because of
the<00:14:37.759> fibroid<00:14:38.759> this<00:14:38.959> is<00:14:39.240> Francis<00:14:40.240> she<00:14:40.399> was
the fibroid this is Francis she was
the fibroid this is Francis she was
diagnosed<00:14:41.199> with<00:14:41.360> a<00:14:41.720> grapefruit<00:14:42.560> size<00:14:42.959> fibroid
diagnosed with a grapefruit size fibroid
diagnosed with a grapefruit size fibroid
this<00:14:43.639> is<00:14:43.759> a<00:14:43.959> big<00:14:44.240> fibroid<00:14:44.920> she<00:14:45.160> was<00:14:45.279> offering
this is a big fibroid she was offering
this is a big fibroid she was offering
hysterctomy<00:14:47.079> but<00:14:47.240> this<00:14:47.320> is<00:14:47.440> an<00:14:47.600> inconceivable
hysterctomy but this is an inconceivable
hysterctomy but this is an inconceivable
proposition<00:14:49.040> for<00:14:49.279> someone<00:14:49.600> who<00:14:49.759> wants<00:14:49.959> to
proposition for someone who wants to
proposition for someone who wants to
keep<00:14:50.279> her<00:14:50.880> pregnancy<00:14:51.440> option<00:14:52.240> so<00:14:52.600> she<00:14:53.160> elected
keep her pregnancy option so she elected
keep her pregnancy option so she elected
to<00:14:54.399> undergo<00:14:54.920> a<00:14:55.040> focused<00:14:55.399> ultrasound
to undergo a focused ultrasound
to undergo a focused ultrasound
procedure<00:14:56.399> in<00:14:56.880> 2008<00:14:57.880> and<00:14:58.000> in<00:14:58.160> 2010<00:14:59.040> she<00:14:59.199> became
procedure in 2008 and in 2010 she became
procedure in 2008 and in 2010 she became
the<00:14:59.680> first<00:14:59.920> time<00:15:00.199> mother<00:15:00.759> to<00:15:01.079> healthy<00:15:01.519> baby<00:15:02.120> so
the first time mother to healthy baby so
the first time mother to healthy baby so
new<00:15:02.600> life<00:15:02.839> was
new life was
new life was
born<00:15:05.759> so<00:15:06.199> in<00:15:06.440> in
born so in in
born so in in
conclusion<00:15:08.959> I<00:15:09.120> I'd<00:15:09.279> like<00:15:09.440> to<00:15:09.560> leave<00:15:09.800> you<00:15:10.040> with
conclusion I I'd like to leave you with
conclusion I I'd like to leave you with
with<00:15:10.600> actually<00:15:10.959> four<00:15:11.440> messages<00:15:12.240> one<00:15:12.519> is<00:15:13.079> think
with actually four messages one is think
with actually four messages one is think
about<00:15:13.680> the<00:15:13.880> amount<00:15:14.560> of<00:15:14.759> suffering<00:15:15.720> that<00:15:15.880> is
about the amount of suffering that is
about the amount of suffering that is
saved<00:15:16.639> from<00:15:17.000> patient<00:15:17.440> undergoing
saved from patient undergoing
saved from patient undergoing
non-invasive<00:15:19.399> surgery<00:15:20.399> and<00:15:20.600> also<00:15:20.959> the
non-invasive surgery and also the
non-invasive surgery and also the
economical<00:15:22.560> and<00:15:22.759> emotional<00:15:23.399> burden<00:15:23.880> removed
economical and emotional burden removed
economical and emotional burden removed
from<00:15:24.600> their<00:15:25.000> families<00:15:25.839> and<00:15:26.240> communities<00:15:27.240> and
from their families and communities and
from their families and communities and
the<00:15:27.959> society<00:15:29.240> at<00:15:29.920> large<00:15:30.920> and<00:15:32.040> um<00:15:33.040> I<00:15:33.160> think<00:15:33.440> also
the society at large and um I think also
the society at large and um I think also
from<00:15:34.160> their<00:15:34.480> Physicians<00:15:35.199> by<00:15:35.360> the<00:15:35.800> way<00:15:36.800> and<00:15:37.480> the
from their Physicians by the way and the
from their Physicians by the way and the
other<00:15:37.959> thing<00:15:38.440> I<00:15:38.519> would<00:15:38.680> like<00:15:38.839> you<00:15:38.959> to<00:15:39.160> think
other thing I would like you to think
other thing I would like you to think
about<00:15:40.360> is<00:15:41.199> the<00:15:41.319> new<00:15:41.600> type<00:15:41.800> of<00:15:41.959> relationship
about is the new type of relationship
about is the new type of relationship
between<00:15:42.920> physician<00:15:43.360> and<00:15:43.600> patients<00:15:44.480> when<00:15:44.639> you
between physician and patients when you
between physician and patients when you
have<00:15:44.959> a<00:15:45.360> patient<00:15:46.360> on<00:15:46.560> the<00:15:46.759> table<00:15:47.480> which<00:15:47.639> is
have a patient on the table which is
have a patient on the table which is
awake<00:15:48.440> and<00:15:48.560> can<00:15:48.759> monitor<00:15:49.639> even<00:15:50.160> you<00:15:50.279> know<00:15:50.440> the
awake and can monitor even you know the
awake and can monitor even you know the
treatment<00:15:51.079> in<00:15:51.199> all<00:15:51.399> our<00:15:51.639> treatment<00:15:52.440> the
treatment in all our treatment the
treatment in all our treatment the
patient<00:15:52.959> holds<00:15:53.240> a<00:15:53.440> stop<00:15:53.680> sonication<00:15:54.360> button
patient holds a stop sonication button
patient holds a stop sonication button
he<00:15:54.800> can<00:15:54.959> stop<00:15:55.240> the<00:15:55.519> surgery<00:15:56.519> you<00:15:56.680> know<00:15:57.000> at<00:15:57.199> any
he can stop the surgery you know at any
he can stop the surgery you know at any
moment<00:15:59.160> and<00:16:00.199> uh<00:16:01.199> with<00:16:01.399> that<00:16:01.600> note<00:16:01.920> I<00:16:02.040> would
moment and uh with that note I would
moment and uh with that note I would
like
like
like
to<00:16:03.920> thank<00:16:04.120> you<00:16:04.279> for
to thank you for
to thank you for
[Applause]
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listening
Yoav Medan, MRI, surgey, medicine, doctor, ultrasound, TED, TED-Ed, TEDEducation, TED, Ed
